abstract：BACKGROUND:Data on psychological distress (DIS), behavioral impact (BI) and health-related quality of life (HRQoL) are important yet lacking among Asian patients with Type 2 diabetes mellitus (T2DM). We aim to identify factors associated with DIS, BI and HRQoL among T2DM to better understand patient needs. METHODS:DIS...

journal_title：Journal of diabetes and its complications

authors： Co MA,Tan LS,Tai ES,Griva K,Amir M,Chong KJ,Lee YS,Lee J,Khoo EY,Wee HL

更新日期：2015-04-01 00:00:00

abstract：:With the rise in childhood obesity, type 2 diabetes mellitus (T2DM) has been recognized to occur in adolescents with increasing frequency. Although much is known about T2DM in adults, few studies have examined the treatment and complications of T2DM in youth. The Treatment Options for type 2 Diabetes in Adolescents an...

journal_title：Journal of diabetes and its complications

authors： Tryggestad JB,Willi SM

更新日期：2015-03-01 00:00:00

abstract：AIMS:Diabetic peripheral neuropathy (DPN) accompanied by painful symptoms is known as painful DPN (pDPN). This study characterized healthcare resource utilization and costs in patients with DPN, pDPN, and severe pDPN relative to diabetes only. METHODS:Four adult cohorts were identified from the Humedica database: type...

journal_title：Journal of diabetes and its complications

authors： Sadosky A,Mardekian J,Parsons B,Hopps M,Bienen EJ,Markman J

更新日期：2015-03-01 00:00:00

abstract：:Painful diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus, affecting, by some estimates, up to one quarter of diabetic patients. Since 2010, no fewer than 5 major international treatment guidelines for painful DPN have been issued, and there are meaningful differences among them. Dulox...

journal_title：Journal of diabetes and its complications

authors： Ziegler D,Fonseca V

更新日期：2015-01-01 00:00:00

abstract：:Recommended low-density lipoprotein cholesterol (LDL-C) levels for patients with documented cardiovascular disease (CVD) are <100mg/dL (2.6mmol/l) with further reduction to <70mg/dL (1.8mmol/l) for higher-risk patients. High-intensity statin treatment may halt the progression as well as stabilize and induce regression...

journal_title：Journal of diabetes and its complications

authors： Athyros VG,Katsiki N,Karagiannis A,Mikhailidis DP

更新日期：2015-01-01 00:00:00

abstract：AIMS:To investigate serum beta2-glycoprotein I-low-density lipoprotein (β2-GPI-LDL) and oxidized low-density lipoprotein (ox-LDL) levels in type 2 diabetes mellitus (T2DM) patients, and to further evaluate the associations of β2-GPI-LDL with ox-LDL in vivo and with the presence of diabetic microvascular complications. ...

journal_title：Journal of diabetes and its complications

authors： Yu R,Yuan Y,Niu D,Song J,Liu T,Wu J,Wang J

更新日期：2015-01-01 00:00:00

abstract：AIMS:Using diabetic foot (DF) as an indicator of severe diabetes, we aimed to investigate the cognitive profile of DF patients and the relations between cognitive functioning and both diabetes complications and comorbidities. METHODS:Dementia-free patients with DF aged 30-90 (n=153) were assessed through medical recor...

journal_title：Journal of diabetes and its complications

authors： Marseglia A,Xu W,Rizzuto D,Ferrari C,Whisstock C,Brocco E,Fratiglioni L,Crepaldi G,Maggi S

更新日期：2014-11-01 00:00:00

abstract：AIM:To evaluate the risk of urinary tract infections (UTI) in subjects with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS:Subjects aged ≥18years and diagnosed with T2DM between 1/1/10 and 12/31/10 were identified using the MarketScan® databases, which are representative of the commercially insured US popula...

journal_title：Journal of diabetes and its complications

authors： Fu AZ,Iglay K,Qiu Y,Engel S,Shankar R,Brodovicz K

更新日期：2014-11-01 00:00:00

abstract：:As the average life expectancy of patients with cystic fibrosis (CF) improves, the long term co-morbidities assume increasing importance. CF related diabetes (CFRD) has adverse effects on both nutrition and pulmonary function, and is associated with increased mortality. Abnormalities of glucose metabolism in CF repres...

journal_title：Journal of diabetes and its complications

authors： Perano S,Rayner CK,Couper J,Martin J,Horowitz M

更新日期：2014-11-01 00:00:00

abstract：AIMS:The efficacy of the once-daily prandial GLP-1 receptor agonist lixisenatide plus basal insulin in T2DM was assessed by pooling results of phase III trials. METHODS:A meta-analysis was performed of results from three trials in the GetGoal clinical program concerning lixisenatide or placebo plus basal insulin with/...

journal_title：Journal of diabetes and its complications

authors： Charbonnel B,Bertolini M,Tinahones FJ,Domingo MP,Davies M

更新日期：2014-11-01 00:00:00

abstract：:There has been a substantial evolution of concepts related to disordered gastric emptying in diabetes. While the traditional focus has hitherto related to the pathophysiology and management of upper gastrointestinal symptoms associated with gastroparesis, it is now apparent that the rate of gastric emptying is central...

journal_title：Journal of diabetes and its complications

authors： Phillips LK,Rayner CK,Jones KL,Horowitz M

更新日期：2014-11-01 00:00:00

abstract：AIMS:Recent studies suggest that circadian rhythms regulate glucose metabolism, weight loss, and even drug efficacy. Moreover, molecules targeted at the circadian clock show promise in treating metabolic disease. Therefore, this study set out to better characterize interactions among diurnal rhythms in prediabetes. ME...

journal_title：Journal of diabetes and its complications

authors： Sonnier T,Rood J,Gimble JM,Peterson CM

更新日期：2014-11-01 00:00:00

abstract：AIMS:The aim of this study is to explore whether administration timing affects glycaemic control by lixisenatide once-daily in type 2 diabetes mellitus (T2DM). METHODS:A phase IIIb, open-label, 1:1 randomized, active-controlled, 24-week multicentre study of T2DM patients inadequately controlled on metformin was conduc...

journal_title：Journal of diabetes and its complications

authors： Ahrén B,Vorokhobina N,Souhami E,Demil N,Ye J,Aronson R

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Current approaches to the management of type 2 diabetes focus on the early initiation of novel pharmacologic therapies and bariatric surgery. OBJECTIVE:The purpose of this study was to revisit the use of intensive, outpatient, behavioral weight management programs for the management of type 2 diabetes. DES...

journal_title：Journal of diabetes and its complications

authors： Rothberg AE,McEwen LN,Kraftson AT,Fowler CE,Herman WH

更新日期：2014-07-01 00:00:00

abstract：AIMS:This study determined the joint association between physical activity, pharmacotherapy, and HbA1c control on all-cause and cardiovascular disease (CVD) mortality risk in adults with and without type 2 diabetes (T2D). METHODS:12,060 adults from NHANES III and NHANES continuous (1999-2002) surveys were used. Cox pr...

journal_title：Journal of diabetes and its complications

authors： Brown RE,Riddell MC,Macpherson AK,Canning KL,Kuk JL

更新日期：2014-05-01 00:00:00

abstract：AIMS:We assessed the relative associations of β-cell dysfunction and insulin sensitivity with baseline glycemic status and incident glycemic progression among Asian Indians in the United States. METHODS:A 5-sample oral glucose tolerance test was obtained at baseline. Normoglycemia, impaired fasting glucose (IFG), impa...

journal_title：Journal of diabetes and its complications

authors： Gujral UP,Narayan KM,Kahn SE,Kanaya AM

更新日期：2014-01-01 00:00:00

abstract：AIM:To determine the associations between insulin resistance, fibroblast growth factor 23 (FGF-23), and coronary artery calcification (CAC) in chronic kidney disease (CKD) patients. INTRODUCTION:FGF-23 is associated with atherosclerosis and cardiovascular disease, but its association with insulin resistance in CKD has...

journal_title：Journal of diabetes and its complications

authors： Garland JS,Holden RM,Ross R,Adams MA,Nolan RL,Hopman WM,Morton AR

更新日期：2014-01-01 00:00:00

abstract：AIMS:To develop and validate prediction equations to identify individuals at high risk for type 2 diabetes using existing health plan data. METHODS:Health plan data from 2005 to 2009 from 18,527 members of a Midwestern HMO without diabetes, 6% of whom had fasting plasma glucose (FPG) ≥110mg/dL, and health plan data fr...

journal_title：Journal of diabetes and its complications

authors： McEwen LN,Adams SR,Schmittdiel JA,Ferrara A,Selby JV,Herman WH

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Evidence indicates an early neural injury of the retinal cells in diabetes. The aim of the current study was to investigate the apoptosis of the retinal cells and the relationship with CGRP. MATERIALS AND METHODS:The diabetes was induced by treatment of STZ, using which the apoptosis of retinal cells, the c...

journal_title：Journal of diabetes and its complications

authors： Yang JH,Guo Z,Zhang T,Meng XX,Sun T,Wu J

更新日期：2013-11-01 00:00:00

abstract：AIMS:To evaluate whether increased urinary orosomucoid excretion rate (UOER) is an independent predictor of cardiovascular and all-cause mortality in type 2 diabetes (T2DM) and type 1 diabetes (T1DM) at 10years of follow-up. METHOD:We followed 430 patients with T2DM and 148 patients with T1DM until emigration, death o...

journal_title：Journal of diabetes and its complications

authors： Svendstrup M,Christiansen MS,Magid E,Hommel E,Feldt-Rasmussen B

更新日期：2013-11-01 00:00:00

abstract：AIMS:To analyze the seasonal variations in A1c levels among a southern European diabetic population. METHODS:We examined all monthly-grouped A1c determinations from diabetic patients during the period 2006-2011, in a region of southern Spain. RESULTS:There were 61,329 records available. The mean A1c value was 56mmol/...

journal_title：Journal of diabetes and its complications

authors： Gomez-Huelgas R,Santamaria-Fernandez S,Guijarro-Merino R,Navajas-Luque F,Tinahones FJ,Roman-Teran CM,Picon MJ,Bernal-Lopez MR

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Vulvovaginitis, balanitis, and related genital infections are common in patients with type 2 diabetes. Glucosuria, which is an outcome of treatment with sodium glucose cotransporter 2 (SGLT2) inhibitors, is among the possible causes. Dapagliflozin, an SGLT2 inhibitor with demonstrated glycemic benefits in pa...

journal_title：Journal of diabetes and its complications

authors： Johnsson KM,Ptaszynska A,Schmitz B,Sugg J,Parikh SJ,List JF

更新日期：2013-09-01 00:00:00

abstract：AIMS:To estimate the prevalence of symptoms suggestive of gastroparesis and their association to clinical and demographic data in a large population of patients with diabetes mellitus and in the general population in Israel. METHODS:A cross-sectional survey of type 2 diabetic patients treated in community settings was...

journal_title：Journal of diabetes and its complications

authors： Dickman R,Kislov J,Boaz M,Ron Y,Beniashvili Z,Raz I,Baigel I,Niv Y,Wainstein J

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:Little is known about serum concentrations of Matrix Metalloproteinase-9 (MMP-9), MMP-2, TIMP-1 and TIMP-2 in diabetic patients with foot ulcers. This study demonstrates their relationship with wound healing. METHODS:Ninety-four patients with diabetic foot ulcers were recruited in the study. Serum MMP-9, MMP...

journal_title：Journal of diabetes and its complications

authors： Li Z,Guo S,Yao F,Zhang Y,Li T

更新日期：2013-07-01 00:00:00

abstract：:This work presents a systematic review of long-term risk assessment models for evaluating the probability of developing complications in diabetes patients. Diabetes mellitus can cause many complications if not adequately controlled; risk assessment models can help physicians and patients in identifying the complicatio...

journal_title：Journal of diabetes and its complications

authors： Lagani V,Koumakis L,Chiarugi F,Lakasing E,Tsamardinos I

更新日期：2013-07-01 00:00:00

abstract：AIM:To evaluate the efficacy, safety, and tolerability of multiple doses of ipragliflozin. This novel selective inhibitor of sodium glucose co-transporter 2 is in clinical development for the treatment of patients with type 2 diabetes mellitus (T2DM). METHODS:In a 12-week, multicenter, double-blind, randomized, active...

journal_title：Journal of diabetes and its complications

authors： Fonseca VA,Ferrannini E,Wilding JP,Wilpshaar W,Dhanjal P,Ball G,Klasen S

更新日期：2013-05-01 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) significantly increases morbidity and mortality from cardiovascular disease (CVD). Treatments for patients with T2DM have the potential to reduce cardiovascular (CV) risk. This review focuses on the potential of a new class of antidiabetic agents, the sodium glucose cotransporter 2 (SGL...

journal_title：Journal of diabetes and its complications

authors： Basile JN

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of a negative insulinogenic index (change in plasma insulin/change in plasma glucose from 0 to 30 min) from an oral glucose tolerance test according to glucose tolerance category. MATERIALS AND METHODS:Data from the San Antonio Heart Study (n=2494), Japanese American Community Dia...

journal_title：Journal of diabetes and its complications

authors： Faulenbach MV,Wright LA,Lorenzo C,Utzschneider KM,Goedecke JH,Fujimoto WY,Boyko EJ,McNeely MJ,Leonetti DL,Haffner SM,Kahn SE,American Diabetes Association GENNID Study Group.

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes (T1DM) is a pro-inflammatory state characterized by high C-reactive protein (CRP) levels. However, there is a paucity of data examining the role of CRP in promoting the pro-inflammatory state of diabetes. Thus, we examined the pro-inflammatory effects of human CRP using spontaneously diabetic ...

journal_title：Journal of diabetes and its complications

authors： Jialal I,Kaur H,Devaraj S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In this study we evaluated the association of baseline levels of six different candidate proteins for the development of microalbuminuria and macroalbuminuria in type 1 diabetic patients, who were followed for approximately 30 years. Two of the proteins are markers of inflammation: serum amyloid A (SAA) and ...

journal_title：Journal of diabetes and its complications

authors： Overgaard AJ,McGuire JN,Hovind P,Parving HH,Rossing P,Pociot F

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:This study was to observe the difference in one-hour postload plasma glucose levels and analyze its related factors in abdominally obese men with normal glucose tolerance (NGT). DESIGN:This case-control study included 36 abdominally obese men (waist circumference ≥90 cm) and 31 non-abdominally obese men (wai...

journal_title：Journal of diabetes and its complications

authors： Qin CM,Wang R,Yin FZ,Liu B,Ma CM,Lu Q

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:What is the prognostic significance of achieving a systolic blood pressure of <140 mmHg? SETTING:Diabetic renal policlinic, university hospital of Lund, Sweden. SUBJECTS:118 type 2 diabetic patients with micro-macroalbuminuria were followed for four years (range 1-8 years). METHOD AND MAIN OUTCOME MEASURES...

journal_title：Journal of diabetes and its complications

authors： Torffvit O

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:Obesity is known to be an important risk factor for type 2 diabetes and its related comorbid conditions; however, its specific impact on generic health-related quality of life (HRQL) is less clear. The objective of this study was to estimate the association between body mass index (BMI) and HRQL in individua...

journal_title：Journal of diabetes and its complications

authors： Hunger M,Schunk M,Meisinger C,Peters A,Holle R

更新日期：2012-09-01 00:00:00

abstract：AIMS:To observe the natural history of hand function during a two-year period in participants with hand syndromes associated with diabetes and to determine factors related to changing function. METHODS:Hand function was measured over three annual visits using Disability of the Arm, Shoulder and Hand (DASH) and SF-36v2...

journal_title：Journal of diabetes and its complications

authors： Redmond CL,Bain GI,Laslett LL,McNeil JD

更新日期：2012-07-01 00:00:00

abstract：INTRODUCTION:Diabetic polyneuropathy aetiology is based on oxidative stress generation due to production of reactive oxygen species. Ubiquinone is reduced to ubiquinol and redistributed into lipoproteins, possibly to protect them from oxidation. AIMS:To evaluate the impact of oral ubiquinone in diabetic polyneuropathy...

journal_title：Journal of diabetes and its complications

authors： Hernández-Ojeda J,Cardona-Muñoz EG,Román-Pintos LM,Troyo-Sanromán R,Ortiz-Lazareno PC,Cárdenas-Meza MA,Pascoe-González S,Miranda-Díaz AG

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Digital toe amputation is a relatively minor surgical procedure but there is a historical view that it is the "first stage in a predictable clinical course" leading to eventual limb loss. There is a paucity of contemporaneous data on the long-term outcomes of patients undergoing toe amputation. We aim to stu...

journal_title：Journal of diabetes and its complications

authors： Griffin KJ,Rashid TS,Bailey MA,Bird SA,Bridge K,Scott JD

更新日期：2012-05-01 00:00:00

abstract：AIMS:To investigate about serum PCT, IL-6 and IL-8 levels and how they are affected by the treatment in diabetic foot patients. METHODS:Fifty patients' blood samples were taken to study ESR and CRP, IL-6, IL-8 and PCT before and at the 14th day of the treatment. RESULTS:The pretreatment results of the 50 patients sho...

journal_title：Journal of diabetes and its complications

authors： Altay FA,Sencan İ,Şentürk GÇ,Altay M,Güvenman S,Ünverdi S,Açıkgöz ZC

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:We aim to determine whether healthcare costs for patients diagnosed with Type 2 Diabetes Mellitus (T2DM) are associated with the severity of diabetes complications as measured by the Diabetes Complication Severity Index (DCSI). METHODS:Retrospective cohort analysis was performed on a 2007 primary care cohort...

journal_title：Journal of diabetes and its complications

authors： Wu CX,Tan WS,Toh MP,Heng BH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:A quantifiable assessment of socioeconomic status and its bearing on clinical outcome in patients with diabetes is lacking. The social adaptability index (SAI) has previously been validated in the general population and in patients with chronic kidney disease, including those on dialysis and with kidney tran...

journal_title：Journal of diabetes and its complications

authors： Goldfarb-Rumyantzev AS,Rout P,Sandhu GS,Barenbaum A,Patibandla BK,Narra A,Chawla V,Williams M

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:The purpose was to assess the activity of nuclear factor (NF)-κB and hypoxia inducible factor (HIF)-1α transcription factors and the expression levels of inflammation markers [interleukin (IL)-6 and IL-8] in the vitreous of patients suffering from proliferative diabetic retinopathy (PDR) scheduled for elective ...

journal_title：Journal of diabetes and its complications

authors： Arjamaa O,Pöllönen M,Kinnunen K,Ryhänen T,Kaarniranta K

更新日期：2011-11-01 00:00:00